Daya Hambat Krim Minyak Atsiri Herba Boborangan (Hyptis brevipes) sebagai antibakteri terhadap Staphylococcus aureus
DOI:
https://doi.org/10.29303/jstl.v7i1.204Keywords:
antibacterial, cream, essential oil, Hyptis brevipes, Staphylococcus aureusAbstract
Boborongan (Hyptis brevipes) is empirically used in ethnomedicine containing of essential oil which it is applied to inhibit the growth of the Staphyllococcus aureus. Cream preparation along with oil in water emulsion is often applied due to easiness and compliance particulary for cosmetic and aesthetic use. This study aimed to determine the minimum inhibitory concentration of cream based essential oil of Hyptis brevipes against Staphylococcus aureus. Essential oil from Hyptis brevipes was isolated using the water vapor distillation method. Cream based essential oil of Hyptis brevipes of 0.1%, 0.2%, and 0.4%, respectively. Antibacterial activity study was carried out using a well diffusion method. Antibacterial inhibition was obtained by measuring the clear zone on the medium. The results of the antibacterial inhibition test showed that the cream based Hyptis brevipes essential oil along with concentration of 0.1%, 0.2%, and 0.4% showed antibacterial activity with the diameter of inhibition zone are 5.3 mm; 5.1 mm; and 6 mm, respectively. Therefore, it prooved that the essential oil of Hyptis brevipes was a promising candidate for antibacterial substanceReferences
Aisyah, A. N., Yusuf, N. A. 2017. Formulasi Emulgel Ekstrak Etanol Daun Murbei ( Morus alba L .) Dengan Variasi Konsentrasi Emulgator Span 80 ® dan Tween 80 ®’. Journal of Pharmaceutical and Medicinal Sciences. 2(2): 77–80.
Arham, S., Khumaidi, A., Pitopang, R. 2016. Keanekaragaman jenis tumbuhan obat tradisional dan pemanfaatannya pada suku kulawi di desa mataue kawasan taman nasional lore lindu. Jurnal Biocelebes. 10(2): 01–16.
Kurniawan, M. F., Sugihartini, N., Yuwono, T. 2018. Permeabilitas dan Karakteristik Fisik Emulgel Minyak Atsiri Bunga Cengkeh dengan Penambahan Enhancer. Medical Sains: Junal Ilmiah Kefarmasian. 3(1): 1–10.
Mahanani, A.U. 2018. Studi Potensi Gulma Sebagai Tanaman Obat di Kabupaten Jayawijaya. Agrotek. 4(7): 31–37.
Nofriyanti, Wildani. 2019. Formulasi Krim Dari Ekstrak Air Daun Alpukat ( Persea americana Mill .) Sebagai Sediaan Anti Jerawat. Jurnal Penelitian Farmasi Indonesia. 7(2): 51–56.
Panuluh, P.D. 2019. Potensi Cengkeh (Syzigium aromaticum) sebagai Antibakteri Methicillin Resistant Staphylococcus aureus (MRSA). Jurnal Ilmiah Kesehatan Sandi Husada. 10(2): 270–274.
Roosita, K., Kusharto, C.M., Sekiyama, M., Fachrurozi, Y., Ohtsuka, R. 2008. Medicinal plants used by the villagers of a Sundanese community in West Java, Indonesia. Journal of Ethnopharmacology. 115(1): 72–81.
Royyani, M.F., Rahayu, M. 2016. Pengetahuan Lokal Tumbuhan Obat Masyarakat Desa Dompo-Dompo Jaya, Pulau Wawonii - Sulawesi Tenggara. Jurnal Teknologi Lingkungan, 11(2): 157-166
Savitri, A.A. 2016. Formulasi Sediaan Krim Ekstrak Etanol Buah Mahkota Dewa (Phaleria macrocarpa (Scheff.)Boerl) dengan basis vanishing cream dan uji aktivitas antibakteri terhadap Staphylococcus epidermidis. Naskah publikasi. Universitas Muhammadiyah Surakarta. Surakarta
Tong, S.Y.C., Davis, J.S., Eichenberger, E., Holland, T.L., Fowler, Jr. V.G., 2015. Staphylococcus aureus infections: Epidemiology, pathophysiology, clinical manifestations, and management. Clinical Microbiology Reviews. 28(3): 603–661.
Wahyono, S. Wahyono, S., Widowati, L., Mujahid, R., Subositi, D., Widiyastuti, Y., Haryanti, S., Junediono, Jokopriyambodo, W., Budiarti, M., Maruzy, A., Indrian M, F., Sari, A.N. 2012. Eksplorasi Pengetahuan Lokal Etnomedisin. Lembaga Penerbitan Badan Litbangkes, Jakarta.
Wiguna, P.A. 2016. Formulasi Sediaan Krim Minyak Atsiri Kayu Manis (Cinnamomum burmannii) dengan Basis Vanishing Cream dan Uji Aktivitas Antibakterinya Terhadap Staphylococcus Epidermidis. Naskah publikasi. Universitas Muhammadiyah Surakarta. Surakarta
Xu, D.H., Huang, Y.S., Jiang, D.Q., Yuan, K. 2013. The essential oils chemical compositions and antimicrobial, antioxidant activities and toxicity of three Hyptis species. Pharmaceutical Biology. 51(9):1125–1130.
Yustica, F.K., Widiastuti, N.I., Sapitri, N., Fitriastuti, D. 2019. Essential oils from Alpinia purpurata (Zingiberaceae): Chemical composition and Formulation of antiacne cream. Indonesian Journal of Chemical Research. 4(1): 14–21.
1.png)
